Glycogen Synthase Kinase-3 and Mammalian Target of Rapamycin Pathways Contribute to DNA Synthesis, Cell Cycle Progression, and Proliferation in Human Islets

OBJECTIVE—Our previous studies demonstrated that nutrient regulation of mammalian target of rapamycin (mTOR) signaling promotes regenerative processes in rodent islets but rarely in human islets. Our objective was to extend these findings by using therapeutic agents to determine whether the regulati...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Remedi, Maria S., Pappan, Kirk L., Kwon, Guim, Rohatgi, Nidhi, Marshall, Connie A., McDaniel, Michael L.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646065/
https://www.ncbi.nlm.nih.gov/pubmed/19073772
http://dx.doi.org/10.2337/db07-1208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646065/
https://www.ncbi.nlm.nih.gov/pubmed/19073772
http://dx.doi.org/10.2337/db07-1208

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