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Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

OBJECTIVE—Insulin secretion involves complex events in which the mitochondria play a pivotal role in the generation of signals that couple glucose detection to insulin secretion. Studies on the mitochondrial generation of reactive oxygen species (ROS) generally focus on chronic nutrient exposure. He...

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Detalles Bibliográficos
Autores principales: Leloup, Corinne, Tourrel-Cuzin, Cécile, Magnan, Christophe, Karaca, Melis, Castel, Julien, Carneiro, Lionel, Colombani, Anne-Laure, Ktorza, Alain, Casteilla, Louis, Pénicaud, Luc
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646066/
https://www.ncbi.nlm.nih.gov/pubmed/19073765
http://dx.doi.org/10.2337/db07-1056