Reduced Adipose Tissue Oxygenation in Human Obesity: Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response

OBJECTIVE— Based on rodent studies, we examined the hypothesis that increased adipose tissue (AT) mass in obesity without an adequate support of vascularization might lead to hypoxia, macrophage infiltration, and inflammation. RESEARCH DESIGN AND METHODS— Oxygen partial pressure (AT pO(2)) and AT te...

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Detalles Bibliográficos
Autores principales: Pasarica, Magdalena, Sereda, Olga R., Redman, Leanne M., Albarado, Diana C., Hymel, David T., Roan, Laura E., Rood, Jennifer C., Burk, David H., Smith, Steven R.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646071/
https://www.ncbi.nlm.nih.gov/pubmed/19074987
http://dx.doi.org/10.2337/db08-1098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646071/
https://www.ncbi.nlm.nih.gov/pubmed/19074987
http://dx.doi.org/10.2337/db08-1098

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