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The Distribution of Fitness Effects of Beneficial Mutations in Pseudomonas aeruginosa
Understanding how beneficial mutations affect fitness is crucial to our understanding of adaptation by natural selection. Here, using adaptation to the antibiotic rifampicin in the opportunistic pathogen Pseudomonas aeruginosa as a model system, we investigate the underlying distribution of fitness...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646133/ https://www.ncbi.nlm.nih.gov/pubmed/19266075 http://dx.doi.org/10.1371/journal.pgen.1000406 |