RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1

The human cytidine deaminase APOBEC3G (A3G) is a potent inhibitor of retroviruses and transposable elements and is able to deaminate cytidines to uridines in single-stranded DNA replication intermediates. A3G contains two canonical cytidine deaminase domains (CDAs), of which only the C-terminal one...

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Detalles Bibliográficos
Autores principales: Huthoff, Hendrik, Autore, Flavia, Gallois-Montbrun, Sarah, Fraternali, Franca, Malim, Michael H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646141/
https://www.ncbi.nlm.nih.gov/pubmed/19266078
http://dx.doi.org/10.1371/journal.ppat.1000330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646141/
https://www.ncbi.nlm.nih.gov/pubmed/19266078
http://dx.doi.org/10.1371/journal.ppat.1000330

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