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RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1

The human cytidine deaminase APOBEC3G (A3G) is a potent inhibitor of retroviruses and transposable elements and is able to deaminate cytidines to uridines in single-stranded DNA replication intermediates. A3G contains two canonical cytidine deaminase domains (CDAs), of which only the C-terminal one...

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Detalles Bibliográficos
Autores principales:	Huthoff, Hendrik, Autore, Flavia, Gallois-Montbrun, Sarah, Fraternali, Franca, Malim, Michael H.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646141/ https://www.ncbi.nlm.nih.gov/pubmed/19266078 http://dx.doi.org/10.1371/journal.ppat.1000330

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