Assessment for the identification of better HDAC inhibitor class through binding energy calculations and descriptor analysis

Histone Deacetylase (HDAC) inhibitors represent a budding class of targeted anti-cancer agents. This structurally diverse group of molecules can induce growth arrest, differentiation, apoptosis, and autophagocytic cell death of cancer cells. Of the different classes of HDAC the class I and Class II...

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Detalles Bibliográficos
Autores principales: Subha, Kalyanamoorthy, Kumar, Gopal Ramesh
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2008
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646192/
https://www.ncbi.nlm.nih.gov/pubmed/19255637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646192/
https://www.ncbi.nlm.nih.gov/pubmed/19255637

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