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Assaying the regulatory potential of mammalian conserved non-coding sequences in human cells

BACKGROUND: Conserved non-coding sequences in the human genome are approximately tenfold more abundant than known genes, and have been hypothesized to mark the locations of cis-regulatory elements. However, the global contribution of conserved non-coding sequences to the transcriptional regulation o...

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Detalles Bibliográficos
Autores principales: Attanasio, Catia, Reymond, Alexandre, Humbert, Richard, Lyle, Robert, Kuehn, Michael S, Neph, Shane, Sabo, Peter J, Goldy, Jeff, Weaver, Molly, Haydock, Andrew, Lee, Kristin, Dorschner, Michael, Dermitzakis, Emmanouil T, Antonarakis, Stylianos E, Stamatoyannopoulos, John A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646272/
https://www.ncbi.nlm.nih.gov/pubmed/19055709
http://dx.doi.org/10.1186/gb-2008-9-12-r168