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FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease

BACKGROUND: Candidate single nucleotide polymorphisms (SNPs) from genome-wide association studies (GWASs) were often selected for validation based on their functional annotation, which was inadequate and biased. We propose to use the more than 200,000 microarray studies in the Gene Expression Omnibu...

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Detalles Bibliográficos
Autores principales: Chen, Rong, Morgan, Alex A, Dudley, Joel, Deshpande, Tarangini, Li, Li, Kodama, Keiichi, Chiang, Annie P, Butte, Atul J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646274/
https://www.ncbi.nlm.nih.gov/pubmed/19061490
http://dx.doi.org/10.1186/gb-2008-9-12-r170