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Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence

BACKGROUND: The malaria parasite Plasmodium falciparum exhibits abundant genetic diversity, and this diversity is key to its success as a pathogen. Previous efforts to study genetic diversity in P. falciparum have begun to elucidate the demographic history of the species, as well as patterns of popu...

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Detalles Bibliográficos
Autores principales: Neafsey, Daniel E, Schaffner, Stephen F, Volkman, Sarah K, Park, Daniel, Montgomery, Philip, Milner, Danny A, Lukens, Amanda, Rosen, David, Daniels, Rachel, Houde, Nathan, Cortese, Joseph F, Tyndall, Erin, Gates, Casey, Stange-Thomann, Nicole, Sarr, Ousmane, Ndiaye, Daouda, Ndir, Omar, Mboup, Soulyemane, Ferreira, Marcelo U, Moraes, Sandra do Lago, Dash, Aditya P, Chitnis, Chetan E, Wiegand, Roger C, Hartl, Daniel L, Birren, Bruce W, Lander, Eric S, Sabeti, Pardis C, Wirth, Dyann F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646275/
https://www.ncbi.nlm.nih.gov/pubmed/19077304
http://dx.doi.org/10.1186/gb-2008-9-12-r171