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Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy
We have developed a global strategy based on the Bayesian network framework to prioritize the functional modules mediating genetic perturbations and their phenotypic effects among a set of overlapping candidate modules. We take lethality in Saccharomyces cerevisiae and human cancer as two examples t...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646278/ https://www.ncbi.nlm.nih.gov/pubmed/19087245 http://dx.doi.org/10.1186/gb-2008-9-12-r174 |