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Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane
Mechanisms controlling the disassembly of ezrin/radixin/moesin (ERM) proteins, which link the cytoskeleton to the plasma membrane, are incompletely understood. In lymphocytes, chemokine (e.g., SDF-1) stimulation inactivates ERM proteins, causing their release from the plasma membrane and dephosphory...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646552/ https://www.ncbi.nlm.nih.gov/pubmed/19204146 http://dx.doi.org/10.1083/jcb.200807047 |