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Phospholipase C–mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

Mechanisms controlling the disassembly of ezrin/radixin/moesin (ERM) proteins, which link the cytoskeleton to the plasma membrane, are incompletely understood. In lymphocytes, chemokine (e.g., SDF-1) stimulation inactivates ERM proteins, causing their release from the plasma membrane and dephosphory...

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Detalles Bibliográficos
Autores principales:	Hao, Jian-Jiang, Liu, Yin, Kruhlak, Michael, Debell, Karen E., Rellahan, Barbara L., Shaw, Stephen
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646552/ https://www.ncbi.nlm.nih.gov/pubmed/19204146 http://dx.doi.org/10.1083/jcb.200807047

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