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Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

Epithelial–mesenchymal transition (EMT) is required for mesodermal differentiation during development. The zinc-finger transcription factor, Snail1, can trigger EMT and is sufficient to transcriptionally reprogram epithelial cells toward a mesenchymal phenotype during neoplasia and fibrosis. Whether...

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Detalles Bibliográficos
Autores principales: Rowe, R. Grant, Li, Xiao-Yan, Hu, Yuexian, Saunders, Thomas L., Virtanen, Ismo, de Herreros, Antonio Garcia, Becker, Karl-Friedrich, Ingvarsen, Signe, Engelholm, Lars H., Bommer, Guido T., Fearon, Eric R., Weiss, Stephen J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646556/
https://www.ncbi.nlm.nih.gov/pubmed/19188491
http://dx.doi.org/10.1083/jcb.200810113