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Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs
Epithelial–mesenchymal transition (EMT) is required for mesodermal differentiation during development. The zinc-finger transcription factor, Snail1, can trigger EMT and is sufficient to transcriptionally reprogram epithelial cells toward a mesenchymal phenotype during neoplasia and fibrosis. Whether...
Autores principales: | Rowe, R. Grant, Li, Xiao-Yan, Hu, Yuexian, Saunders, Thomas L., Virtanen, Ismo, de Herreros, Antonio Garcia, Becker, Karl-Friedrich, Ingvarsen, Signe, Engelholm, Lars H., Bommer, Guido T., Fearon, Eric R., Weiss, Stephen J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646556/ https://www.ncbi.nlm.nih.gov/pubmed/19188491 http://dx.doi.org/10.1083/jcb.200810113 |
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