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Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity
Cells have evolved a signaling pathway called the spindle assembly checkpoint (SAC) to increase the fidelity of chromosome segregation by generating a “wait anaphase” signal until all chromosomes are properly aligned within the mitotic spindle. It has been proposed that tension generated by the stre...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646557/ https://www.ncbi.nlm.nih.gov/pubmed/19193623 http://dx.doi.org/10.1083/jcb.200808130 |