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Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease

Allogeneic (allo) hematopoietic stem cell transplantation is an effective therapy for hematological malignancies but it is limited by acute graft-versus-host disease (GVHD). Dendritic cells (DC) play a major role in the allo T cell stimulation causing GVHD. Current immunosuppressive measures to cont...

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Detalles Bibliográficos
Autores principales: Wilson, John, Cullup, Hannah, Lourie, Rohan, Sheng, Yonghua, Palkova, Anna, Radford, Kristen J., Dickinson, Anne M., Rice, Alison M., Hart, Derek N.J., Munster, David J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646577/
https://www.ncbi.nlm.nih.gov/pubmed/19171763
http://dx.doi.org/10.1084/jem.20070723