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Identification of c-Src Tyrosine Kinase Substrates Using Mass Spectrometry and Peptide Microarrays

[Image: see text] c-Src tyrosine kinase plays a critical role in signal transduction downstream of growth factor receptors, integrins and G protein-coupled receptors. We used stable isotope labeling with amino acids in cell culture (SILAC) approach to identify additional substrates of c-Src tyrosine...

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Detalles Bibliográficos
Autores principales: Amanchy, Ramars, Zhong, Jun, Molina, Henrik, Chaerkady, Raghothama, Iwahori, Akiko, Kalume, Dario Eluan, Grønborg, Mads, Joore, Jos, Cope, Leslie, Pandey, Akhilesh
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646669/
https://www.ncbi.nlm.nih.gov/pubmed/18698806
http://dx.doi.org/10.1021/pr800198w