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INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men

BACKGROUND: A common SNP upstream of the INSIG2 gene, rs7566605 (g.-10,1025G>C, Chr2:118,552,255, NT_022135.15), was reported to be associated with obesity (Body Mass Index, [BMI]) in a genome-wide association scan using the Framingham Heart Study but has not been reproduced in other cohorts. As...

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Detalles Bibliográficos
Autores principales: Orkunoglu-Suer, Funda E, Gordish-Dressman, Heather, Clarkson, Priscilla M, Thompson, Paul D, Angelopoulos, Theodore J, Gordon, Paul M, Moyna, Niall M, Pescatello, Linda S, Visich, Paul S, Zoeller, Robert F, Harmon, Brennan, Seip, Richard L, Hoffman, Eric P, Devaney, Joseph M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646703/
https://www.ncbi.nlm.nih.gov/pubmed/19105843
http://dx.doi.org/10.1186/1471-2350-9-117