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Structure of the 1,N(2)-Ethenodeoxyguanosine Adduct Opposite Cytosine in Duplex DNA: Hoogsteen Base Pairing at pH 5.2

[Image: see text] The exocyclic 1,N(2)-ethenodeoxyguanosine (1,N(2)-ϵdG) adduct, arising from the reaction of vinyl halides and other vinyl monomers, including chloroacetaldehyde, and lipid peroxidation products with dG, was examined at pH 5.2 in the oligodeoxynucleotide duplex 5′-d(CGCATXGAATCC)-3′...

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Detalles Bibliográficos
Autores principales: Shanmugam, Ganesh, Kozekov, Ivan D., Guengerich, F. Peter, Rizzo, Carmelo J., Stone, Michael P.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646752/
https://www.ncbi.nlm.nih.gov/pubmed/18693701
http://dx.doi.org/10.1021/tx8001466