Electrostatic Interactions Guide the Active Site Face of a Structure-Specific Ribonuclease to Its RNA Substrate

[Image: see text] Restrictocin, a member of the α-sarcin family of site-specific endoribonucleases, uses electrostatic interactions to bind to the ribosome and to RNA oligonucleotides, including the minimal specific substrate, the sarcin/ricin loop (SRL) of 23S−28S rRNA. Restrictocin binds to the SR...

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Detalles Bibliográficos
Autores principales: Plantinga, Matthew J., Korennykh, Alexei V., Piccirilli, Joseph A., Correll, Carl C.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646754/
https://www.ncbi.nlm.nih.gov/pubmed/18672906
http://dx.doi.org/10.1021/bi800592g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646754/
https://www.ncbi.nlm.nih.gov/pubmed/18672906
http://dx.doi.org/10.1021/bi800592g

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