Mismatched and Matched dNTP Incorporation by DNA Polymerase β Proceed via Analogous Kinetic Pathways

[Image: see text] While matched nucleotide incorporation by DNA polymerase β (Pol β) has been well-studied, a true understanding of polymerase fidelity requires comparison of both matched and mismatched dNTP incorporation pathways. Here we examine the mechanism of misincorporation for wild-type (WT)...

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Detalles Bibliográficos
Autores principales: Roettger, Michelle P., Bakhtina, Marina, Tsai, Ming-Daw
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646765/
https://www.ncbi.nlm.nih.gov/pubmed/18717589
http://dx.doi.org/10.1021/bi800689d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646765/
https://www.ncbi.nlm.nih.gov/pubmed/18717589
http://dx.doi.org/10.1021/bi800689d

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