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Escherichia coli MazF Leads to the Simultaneous Selective Synthesis of Both “Death Proteins” and “Survival Proteins”

The Escherichia coli mazEF module is one of the most thoroughly studied toxin–antitoxin systems. mazF encodes a stable toxin, MazF, and mazE encodes a labile antitoxin, MazE, which prevents the lethal effect of MazF. MazF is an endoribonuclease that leads to the inhibition of protein synthesis by cl...

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Detalles Bibliográficos
Autores principales: Amitai, Shahar, Kolodkin-Gal, Ilana, Hananya-Meltabashi, Mirit, Sacher, Ayelet, Engelberg-Kulka, Hanna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646832/
https://www.ncbi.nlm.nih.gov/pubmed/19282968
http://dx.doi.org/10.1371/journal.pgen.1000390