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Total Syntheses of (+)- and (−)-Peribysin E

[Image: see text] A convergent, stereocontrolled route to either antipode of the cell adhesion inhibitor, peribysin E, has been achieved from carvone. Highlights of the synthesis include a Diels−Alder reaction to generate a cis-decalin framework, followed by semipinacol-type ring contraction to secu...

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Detalles Bibliográficos
Autores principales: Angeles, Angie R., Waters, Stephen P., Danishefsky, Samuel J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646880/
https://www.ncbi.nlm.nih.gov/pubmed/18783227
http://dx.doi.org/10.1021/ja8048207