A Kinetic Alignment of Orthologous Inosine-5′-monophosphate Dehydrogenases

[Image: see text] IMP dehydrogenase (IMPDH) catalyzes two very different chemical transformations, a dehydrogenase reaction and a hydrolysis reaction. The enzyme toggles between the open conformation required for the dehydrogenase reaction and the closed conformation of the hydrolase reaction by mov...

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Detalles Bibliográficos
Autores principales: Riera, Thomas V., Wang, Wen, Josephine, Helen R., Hedstrom, Lizbeth
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646883/
https://www.ncbi.nlm.nih.gov/pubmed/18642884
http://dx.doi.org/10.1021/bi800674a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646883/
https://www.ncbi.nlm.nih.gov/pubmed/18642884
http://dx.doi.org/10.1021/bi800674a

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