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Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties

[Image: see text] Polyguanidinium oxanorbornene (PGON) was synthesized from norbornene monomers via ring-opening metathesis polymerization. This polymer was observed to be strongly antibacterial against Gram-negative and Gram-positive bacteria as well as nonhemolytic against human red blood cells. T...

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Detalles Bibliográficos
Autores principales: Gabriel, Gregory J., Madkour, Ahmad E., Dabkowski, Jeffrey M., Nelson, Christopher F., Nüsslein, Klaus, Tew, Gregory N.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646885/
https://www.ncbi.nlm.nih.gov/pubmed/18850741
http://dx.doi.org/10.1021/bm800855t