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Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties
[Image: see text] Polyguanidinium oxanorbornene (PGON) was synthesized from norbornene monomers via ring-opening metathesis polymerization. This polymer was observed to be strongly antibacterial against Gram-negative and Gram-positive bacteria as well as nonhemolytic against human red blood cells. T...
Autores principales: | Gabriel, Gregory J., Madkour, Ahmad E., Dabkowski, Jeffrey M., Nelson, Christopher F., Nüsslein, Klaus, Tew, Gregory N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646885/ https://www.ncbi.nlm.nih.gov/pubmed/18850741 http://dx.doi.org/10.1021/bm800855t |
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