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The A-rich RNA sequences of HIV-1 pol are important for the synthesis of viral cDNA
The bias of A-rich codons in HIV-1 pol is thought to be a record of hypermutations in viral genomes that lack biological functions. Bioinformatic analysis predicted that A-rich sequences are generally associated with minimal local RNA structures. Using codon modifications to reduce the amount of A-r...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647285/ https://www.ncbi.nlm.nih.gov/pubmed/19106143 http://dx.doi.org/10.1093/nar/gkn1015 |