The A-rich RNA sequences of HIV-1 pol are important for the synthesis of viral cDNA

The bias of A-rich codons in HIV-1 pol is thought to be a record of hypermutations in viral genomes that lack biological functions. Bioinformatic analysis predicted that A-rich sequences are generally associated with minimal local RNA structures. Using codon modifications to reduce the amount of A-r...

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Detalles Bibliográficos
Autores principales: Keating, Cameron P., Hill, Melissa K., Hawkes, David J., Smyth, Redmond P., Isel, Catherine, Le, Shu-Yun, Palmenberg, Ann C., Marshall, John A., Marquet, Roland, Nabel, Gary J., Mak, Johnson
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647285/
https://www.ncbi.nlm.nih.gov/pubmed/19106143
http://dx.doi.org/10.1093/nar/gkn1015

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