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Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspective
Type II DNA topoisomerases (topos) are essential and ubiquitous enzymes that perform important intracellular roles in chromosome condensation and segregation, and in regulating DNA supercoiling. Eukaryotic topo II, a type II topoisomerase, is a homodimeric enzyme that solves topological entanglement...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647300/ https://www.ncbi.nlm.nih.gov/pubmed/19155278 http://dx.doi.org/10.1093/nar/gkn1059 |