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Tuning the relative affinities for activating and repressing operators of a temporally regulated restriction-modification system

Most type II restriction-modification (R-M) systems produce separate endonuclease (REase) and methyltransferase (MTase) proteins. After R-M genes enter a new cell, MTase activity must appear before REase or the host chromosome will be cleaved. Temporal control of these genes thus has life-or-death c...

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Detalles Bibliográficos
Autores principales: Mruk, Iwona, Blumenthal, Robert M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647307/
https://www.ncbi.nlm.nih.gov/pubmed/19126580
http://dx.doi.org/10.1093/nar/gkn1010