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Tuning the relative affinities for activating and repressing operators of a temporally regulated restriction-modification system
Most type II restriction-modification (R-M) systems produce separate endonuclease (REase) and methyltransferase (MTase) proteins. After R-M genes enter a new cell, MTase activity must appear before REase or the host chromosome will be cleaved. Temporal control of these genes thus has life-or-death c...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647307/ https://www.ncbi.nlm.nih.gov/pubmed/19126580 http://dx.doi.org/10.1093/nar/gkn1010 |