The Igf2/H19 imprinting control region exhibits sequence-specific and cell-type-dependent DNA methylation-mediated repression

Methylation of CpGs is generally thought to repress transcription without significant influence from the sequence surrounding the methylated dinucleotides. Using the mouse Igf2/H19 imprinting control region (ICR), Igf2r differentially methylated region 2 (DMR2) and bacterial sequences, we addressed...

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Detalles Bibliográficos
Autores principales: Chen, Yinming, Dhupelia, Amrita, Schoenherr, Christopher J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647309/
https://www.ncbi.nlm.nih.gov/pubmed/19074953
http://dx.doi.org/10.1093/nar/gkn985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647309/
https://www.ncbi.nlm.nih.gov/pubmed/19074953
http://dx.doi.org/10.1093/nar/gkn985

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