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Effects of magnesium and related divalent metal ions in topoisomerase structure and function
The catalytic steps through which DNA topoisomerases produce their biological effects and the interference of drug molecules with the enzyme–DNA cleavage complex have been thoroughly investigated both from the biophysical and the biochemical point of view. This provides the basic structural insight...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647314/ https://www.ncbi.nlm.nih.gov/pubmed/19188255 http://dx.doi.org/10.1093/nar/gkp024 |