PSI-BLAST pseudocounts and the minimum description length principle

Position specific score matrices (PSSMs) are derived from multiple sequence alignments to aid in the recognition of distant protein sequence relationships. The PSI-BLAST protein database search program derives the column scores of its PSSMs with the aid of pseudocounts, added to the observed amino a...

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Detalles Bibliográficos
Autores principales: Altschul, Stephen F., Gertz, E. Michael, Agarwala, Richa, Schäffer, Alejandro A., Yu, Yi-Kuo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647318/
https://www.ncbi.nlm.nih.gov/pubmed/19088134
http://dx.doi.org/10.1093/nar/gkn981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647318/
https://www.ncbi.nlm.nih.gov/pubmed/19088134
http://dx.doi.org/10.1093/nar/gkn981

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