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Phylogenomics of DNA topoisomerases: their origin and putative roles in the emergence of modern organisms
Topoisomerases are essential enzymes that solve topological problems arising from the double-helical structure of DNA. As a consequence, one should have naively expected to find homologous topoisomerases in all cellular organisms, dating back to their last common ancestor. However, as observed for o...
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647321/ https://www.ncbi.nlm.nih.gov/pubmed/19208647 http://dx.doi.org/10.1093/nar/gkp032 |