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Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells

BACKGROUND: Neuroblastic tumors (NBT) derive from neural crest stem cells (NCSC). Histologically, NBT are composed by neuroblasts and Schwannian cells. In culture, neuroblastic (N-), substrate-adherent (S-) and intermediate phenotype (I-) cell subtypes arise spontaneously. METHODS: Here, neuroblasto...

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Detalles Bibliográficos
Autores principales: Acosta, Sandra, Lavarino, Cinzia, Paris, Raquel, Garcia, Idoia, de Torres, Carmen, Rodríguez, Eva, Beleta, Helena, Mora, Jaume
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647534/
https://www.ncbi.nlm.nih.gov/pubmed/19216736
http://dx.doi.org/10.1186/1471-213X-9-12