Cloning and characterization of canine PAX6 and evaluation as a candidate gene in a canine model of aniridia

PURPOSE: Mutations in PAX6 cause human aniridia. The small eye (sey) mouse represents an animal model for aniridia. However, no large animal model currently exists. We cloned and characterized canine PAX6, and evaluated PAX6 for causal associations with inherited aniridia in dogs. METHODS: Canine PA...

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Detalles Bibliográficos
Autores principales: Hunter, Linda S., Sidjanin, Duska J., Hijar, Manuel Villagrasa, Johnson, Jennifer L., Kirkness, Ewen, Acland, Gregory M., Aguirre, Gustavo D.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647561/
https://www.ncbi.nlm.nih.gov/pubmed/17417604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647561/
https://www.ncbi.nlm.nih.gov/pubmed/17417604

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