CFTR Is a Negative Regulator of NFκB Mediated Innate Immune Response

BACKGROUND: Dysfunctional CFTR in the airways is associated with elevated levels of NFκB mediated IL-8 signaling leading to neutrophil chemotaxis and chronic lung inflammation in cystic fibrosis. The mechanism(s) by which CFTR mediates inflammatory signaling is under debate. METHODOLOGY/PRINCIPAL FI...

Descripción completa

Detalles Bibliográficos
Autores principales: Vij, Neeraj, Mazur, Steven, Zeitlin, Pamela L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647738/
https://www.ncbi.nlm.nih.gov/pubmed/19247502
http://dx.doi.org/10.1371/journal.pone.0004664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647738/
https://www.ncbi.nlm.nih.gov/pubmed/19247502
http://dx.doi.org/10.1371/journal.pone.0004664

Ejemplares similares