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CFTR Is a Negative Regulator of NFκB Mediated Innate Immune Response

BACKGROUND: Dysfunctional CFTR in the airways is associated with elevated levels of NFκB mediated IL-8 signaling leading to neutrophil chemotaxis and chronic lung inflammation in cystic fibrosis. The mechanism(s) by which CFTR mediates inflammatory signaling is under debate. METHODOLOGY/PRINCIPAL FI...

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Detalles Bibliográficos
Autores principales:	Vij, Neeraj, Mazur, Steven, Zeitlin, Pamela L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647738/ https://www.ncbi.nlm.nih.gov/pubmed/19247502 http://dx.doi.org/10.1371/journal.pone.0004664

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