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Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation

Bone undergoes continuous remodelling throughout adult life, and the equilibrium between bone formation by osteoblasts and bone resorption by osteoclasts defines the final bone mass. Here we show that Snail1 regulates this balance by controlling osteoblast differentiation. Snail1 is necessary for th...

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Detalles Bibliográficos
Autores principales: de Frutos, Cristina A, Dacquin, Romain, Vega, Sonia, Jurdic, Pierre, Machuca-Gayet, Irma, Angela Nieto, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647771/
https://www.ncbi.nlm.nih.gov/pubmed/19197242
http://dx.doi.org/10.1038/emboj.2009.23