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Signaling Logic of Activity-Triggered Dendritic Protein Synthesis: An mTOR Gate But Not a Feedback Switch

Changes in synaptic efficacy are believed to form the cellular basis for memory. Protein synthesis in dendrites is needed to consolidate long-term synaptic changes. Many signals converge to regulate dendritic protein synthesis, including synaptic and cellular activity, and growth factors. The coordi...

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Detalles Bibliográficos
Autores principales: Jain, Pragati, Bhalla, Upinder S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647780/
https://www.ncbi.nlm.nih.gov/pubmed/19242559
http://dx.doi.org/10.1371/journal.pcbi.1000287