Regulation of P450 oxidoreductase by gonadotropins in rat ovary and its effect on estrogen production

BACKGROUND: P450 oxidoreductase (POR) catalyzes electron transfer to microsomal P450 enzymes. Its deficiency causes Antley-Bixler syndrome (ABS), and about half the patients with ABS have ambiguous genitalia and/or impaired steroidogenesis. POR mRNA expression is up-regulated when mesenchymal stem c...

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Detalles Bibliográficos
Autores principales: Inaoka, Yoshihiko, Yazawa, Takashi, Mizutani, Tetsuya, Kokame, Koichi, Kangawa, Kenji, Uesaka, Miki, Umezawa, Akihiro, Miyamoto, Kaoru
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647926/
https://www.ncbi.nlm.nih.gov/pubmed/19077323
http://dx.doi.org/10.1186/1477-7827-6-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647926/
https://www.ncbi.nlm.nih.gov/pubmed/19077323
http://dx.doi.org/10.1186/1477-7827-6-62

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