Cargando…

Regulation of P450 oxidoreductase by gonadotropins in rat ovary and its effect on estrogen production

BACKGROUND: P450 oxidoreductase (POR) catalyzes electron transfer to microsomal P450 enzymes. Its deficiency causes Antley-Bixler syndrome (ABS), and about half the patients with ABS have ambiguous genitalia and/or impaired steroidogenesis. POR mRNA expression is up-regulated when mesenchymal stem c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Inaoka, Yoshihiko, Yazawa, Takashi, Mizutani, Tetsuya, Kokame, Koichi, Kangawa, Kenji, Uesaka, Miki, Umezawa, Akihiro, Miyamoto, Kaoru
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647926/ https://www.ncbi.nlm.nih.gov/pubmed/19077323 http://dx.doi.org/10.1186/1477-7827-6-62

Ejemplares similares

Co-activator p120 is increased by gonadotropins in the rat ovary and enhances progesterone receptor activity
por: Yoshino, Miki, et al.
Publicado: (2006)

Identification of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible genes in human amniotic epithelial cells
por: Abe, Yumiko, et al.
Publicado: (2006)

Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary
por: Imamichi, Yoshitaka, et al.
Publicado: (2017)

Pharmacogenomics of human P450 oxidoreductase
por: Pandey, Amit V., et al.
Publicado: (2014)

Congenital adrenal hyperplasia due to P450 oxidoreductase deficiency
por: Zhang, Jin, et al.
Publicado: (2022)

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
por: Campelo, Diana, et al.
Publicado: (2018)

Stable Chinese Hamster Ovary Suspension Cell Lines Harboring Recombinant Human Cytochrome P450 Oxidoreductase and Human Cytochrome P450 Monooxygenases as Platform for In Vitro Biotransformation Studies
por: Schulz, Christian, et al.
Publicado: (2023)

Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver
por: Zhang, Hai-Feng, et al.
Publicado: (2016)

Application of nanodisc technology for direct electrochemical investigation of plant cytochrome P450s and their NADPH P450 oxidoreductase
por: Bavishi, Krutika, et al.
Publicado: (2016)

Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
por: Jensen, Simon Bo, et al.
Publicado: (2021)

Expression of Estrogen Receptor α 36 (ESR36) in the Hamster Ovary throughout the Estrous Cycle: Effects of Gonadotropins
por: Chakraborty, Prabuddha, et al.
Publicado: (2013)

Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain
por: Hall, Catherine N., et al.
Publicado: (2009)

Prenatal Diagnosis of Congenital Adrenal Hyperplasia Caused by P450 Oxidoreductase Deficiency
por: Reisch, Nicole, et al.
Publicado: (2013)

Cytochrome P450 Oxidoreductase Deficiency: Novel Cause of Ambiguity with Primary Amenorrhea
por: Khadilkar, Kranti Shreesh, et al.
Publicado: (2017)

Role of Lung P450 Oxidoreductase in Paraquat-Induced Collagen Deposition in the Lung
por: Kovalchuk, Nataliia, et al.
Publicado: (2022)

In Silico Analysis of PORD Mutations on the 3D Structure of P450 Oxidoreductase
por: Nurhafizuddin, Muhammad, et al.
Publicado: (2022)

Genotype-Phenotype Analysis in Congenital Adrenal Hyperplasia due to P450 Oxidoreductase Deficiency
por: Krone, Nils, et al.
Publicado: (2012)

Conformational Equilibrium of NADPH–Cytochrome P450 Oxidoreductase Is Essential for Heme Oxygenase Reaction
por: Sugishima, Masakazu, et al.
Publicado: (2020)

Effects of cytochrome P450 oxidoreductase genotypes on the pharmacokinetics of amlodipine in healthy Korean subjects
por: Han, Ji Min, et al.
Publicado: (2020)

Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase
por: Niikura, Mamoru, et al.
Publicado: (2017)

An electron transfer competent structural ensemble of membrane-bound cytochrome P450 1A1 and cytochrome P450 oxidoreductase
por: Mukherjee, Goutam, et al.
Publicado: (2021)

Expression of peroxiredoxin I regulated by gonadotropins in the rat ovary
por: Lee, Yu-Il, et al.
Publicado: (2011)

The Effect of Gonadotropin on Glucose Transport and Apoptosis in Rat Ovary
por: Zhang, Cheng, et al.
Publicado: (2012)

The P450 oxidoreductase, RedA, controls development beyond the mound stage in Dictyostelium discoideum
por: Gonzalez-Kristeller, Daniela C, et al.
Publicado: (2008)

Pubertal Presentation in Seven Patients with Congenital Adrenal Hyperplasia due to P450 Oxidoreductase Deficiency
por: Idkowiak, Jan, et al.
Publicado: (2011)

Modeling of Anopheles minimus Mosquito NADPH-Cytochrome P450 Oxidoreductase (CYPOR) and Mutagenesis Analysis
por: Sarapusit, Songklod, et al.
Publicado: (2013)

Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation
por: El-Serafi, Ibrahim, et al.
Publicado: (2015)

Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals
por: Rendic, Slobodan, et al.
Publicado: (2014)

Clinical, endocrinological, and molecular features of four Korean cases of cytochrome P450 oxidoreductase deficiency
por: Lee, Yena, et al.
Publicado: (2020)

Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC)
por: Acharya, Kelly S., et al.
Publicado: (2020)

MON-060 P-450 Oxidoreductase Deficiency with Antley Bixler Phenotype: A Novel Mutation
por: Kumar, Anshul, et al.
Publicado: (2020)

Immunoreactivities of androgen receptor, estrogen receptors, p450arom, p450c17 proteins in wild ground squirrels ovaries during the nonbreeding and breeding seasons
por: Li, Xiaonan, et al.
Publicado: (2012)

An Unusual Presentation of Ovarian Fibroma Originating from an Autoamputated Ovary
por: Yazawa, Hiroyuki, et al.
Publicado: (2019)

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency
por: Tomalik-Scharte, Dorota, et al.
Publicado: (2010)

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism
por: Barzi, Mercedes, et al.
Publicado: (2017)

The role of gonadotropin‐releasing hormone neurons in polycystic ovary syndrome
por: McCartney, Christopher R., et al.
Publicado: (2022)

Association Between a Tri-allelic Polymorphism in the Estrogen Metabolism Oxidoreductase NRH:Quinone Oxidoreductase 2 Gene and Risk of Breast Cancer by Molecular Subtype
por: Zhou, Jiao-Qun, et al.
Publicado: (2021)

Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism
por: Esteves, Francisco, et al.
Publicado: (2023)

Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic Cells
por: Yazawa, Takashi, et al.
Publicado: (2019)

Amphipol-facilitated elucidation of the functional tetrameric complex of full-length cytochrome P450 CYP2B4 and NADPH-cytochrome P450 oxidoreductase
por: Cheng, Shen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9q5v6k93i3cbmopl5eh3kpkb50