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Shape-IT: new rapid and accurate algorithm for haplotype inference

BACKGROUND: We have developed a new computational algorithm, Shape-IT, to infer haplotypes under the genetic model of coalescence with recombination developed by Stephens et al in Phase v2.1. It runs much faster than Phase v2.1 while exhibiting the same accuracy. The major algorithmic improvements r...

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Detalles Bibliográficos
Autores principales: Delaneau, Olivier, Coulonges, Cédric, Zagury, Jean-François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647951/
https://www.ncbi.nlm.nih.gov/pubmed/19087329
http://dx.doi.org/10.1186/1471-2105-9-540