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A random forest approach to the detection of epistatic interactions in case-control studies

BACKGROUND: The key roles of epistatic interactions between multiple genetic variants in the pathogenesis of complex diseases notwithstanding, the detection of such interactions remains a great challenge in genome-wide association studies. Although some existing multi-locus approaches have shown the...

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Detalles Bibliográficos
Autores principales: Jiang, Rui, Tang, Wanwan, Wu, Xuebing, Fu, Wenhui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648748/
https://www.ncbi.nlm.nih.gov/pubmed/19208169
http://dx.doi.org/10.1186/1471-2105-10-S1-S65