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DNA motif alignment by evolving a population of Markov chains

BACKGROUND: Deciphering cis-regulatory elements or de novo motif-finding in genomes still remains elusive although much algorithmic effort has been expended. The Markov chain Monte Carlo (MCMC) method such as Gibbs motif samplers has been widely employed to solve the de novo motif-finding problem th...

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Detalles Bibliográficos
Autor principal: Bi, Chengpeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648755/
https://www.ncbi.nlm.nih.gov/pubmed/19208112
http://dx.doi.org/10.1186/1471-2105-10-S1-S13