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Partial correlation analysis indicates causal relationships between GC-content, exon density and recombination rate in the human genome

BACKGROUND: Several features are known to correlate with the GC-content in the human genome, including recombination rate, gene density and distance to telomere. However, by testing for pairwise correlation only, it is impossible to distinguish direct associations from indirect ones and to distingui...

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Detalles Bibliográficos
Autores principales: Freudenberg, Jan, Wang, Mingyi, Yang, Yaning, Li, Wentian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648766/
https://www.ncbi.nlm.nih.gov/pubmed/19208170
http://dx.doi.org/10.1186/1471-2105-10-S1-S66