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ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules

BACKGROUND: The detection of cis-regulatory modules (CRMs) that mediate transcriptional responses in eukaryotes remains a key challenge in the postgenomic era. A CRM is characterized by a set of co-occurring transcription factor binding sites (TFBS). In silico methods have been developed to search f...

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Detalles Bibliográficos
Autores principales: Sun, Hong, De Bie, Tijl, Storms, Valerie, Fu, Qiang, Dhollander, Thomas, Lemmens, Karen, Verstuyf, Annemieke, De Moor, Bart, Marchal, Kathleen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648767/
https://www.ncbi.nlm.nih.gov/pubmed/19208131
http://dx.doi.org/10.1186/1471-2105-10-S1-S30