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Genome-scale analysis to the impact of gene deletion on the metabolism of E. coli: constraint-based simulation approach
BACKGROUND: Genome-scale models of metabolism have only been analyzed with the constraint-based modelling philosophy. Some gene deletion studies on in silico organism models at genome-scale have been made, but most of them were from the aspects of distinguishing lethal and non-lethal genes or growth...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648778/ https://www.ncbi.nlm.nih.gov/pubmed/19208166 http://dx.doi.org/10.1186/1471-2105-10-S1-S62 |